Hemophilia is a bleeding disorder caused by a defective of the chromosomes. Hemophilia happens when ones inherits problems with certain blood-clotting factors. Hemophilia occurs in 2 forms, hemophilia A and B. In both forms, a factor gets defected. The defective factor interferes with the ability of the body to produce the clotting factors that allow for normal clotting.

There are symptoms of Hemophillia. There are :
• Spontaneous bleeding after an injury

• Bleeding in urine and stool

• Prolonged bleeding after the umbilical cord is cut at birth

• Bleeding into joints and associated pain and swelling

• Bleeding in muscle

• Bleeding after dental work

The common treatment for hemophilia is replacing the clotting factor that is too low or missing. We use two clotting factors in replacement therapy which comes from two sources: one clotting factor products are derived from human blood plasma. Clotting factors from human blood plasma have a little chance of being polluted with viruses such as HIV and hepatitis; therefore we use the other recombinant DNA technique. This process is carried out in aseptic production facilities where the clotting factor factors are grown synthetically.

Leukemia is derived from Greek, which means “white blood” occurs when there is an excess of abnormal white blood cells in the blood. The disease usually starts in the white blood cells. The blood-forming (hematopoietic) cells of the bone marrow make leukocytes to defend the body against infectious organisms, such as viruses and bacteria. If the cells reach the central nervous system and build up in the cerebrospinal fluid that support s the brain and spinal column, they can cause headaches and seizures.

The causes of leukemia is still unknown, but there are symptoms of leukemia including:

• Fever , chills, and other flu-like symptoms.
• Neurological symptoms ( headache ).
• Night sweats
• Swollen or bleeding gums.
• Loss of appetite and/or weight.
• Enlarged liver and spleen.
• Weakness and fatigue.
• Frequent infections.
• Bone pain or tenderness.

Shortness of breath when you’re physically active, as while climbing steps.
The treatments of leukemia can be taken by medicines to kill the abnormal cells. Chemotherapy can be taken by mouth, by shots, or given into a vein (intravenously). Surgery also needed to remove an enlarged spleen or to install a venous acces device to give medication and withdraw blood samples. To kill the abnormal cells can be taken a high-energy x rays.

After radiation and chemotherapy kills the abnormal bone marrow, healthy bone marrow from a healthy donor is given to a patient through a vein. The healthy bone marrow goes to the patient’s bones and makes healthy blood cells. Most children with leukemia will not need a bone marrow transplant.

Some people with leukemia choose to enroll in clinical trials to try out experimental treatments or new combinations of known therapies.